Synthesis and biological screening of 4-(3,3-dimethylspiro{bicyclo[2.2.1]heptan-2,5′-isoxazoline-2}- 3′-yl)-2-aryl-2,3-dihydro-1H-1,5-benzodiazepines

Naqvi, Tahira and Mahajan, Deepali and Sharma, Rattan Lal and Khan, Inshad Ali and Kapoor, Kamal K. (2010) Synthesis and biological screening of 4-(3,3-dimethylspiro{bicyclo[2.2.1]heptan-2,5′-isoxazoline-2}- 3′-yl)-2-aryl-2,3-dihydro-1H-1,5-benzodiazepines. Journal of Heterocyclic Chemistry, 48 (1). pp. 144-148. ISSN 0022152X

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Official URL: http://dx.doi.org/10.1002/jhet.194

Abstract

A series of novel 4-(3,3-dimethylspiro{bicyclo[2.2.1]heptan-2,50-isoxazoline-2}-30-yl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepines were synthesized. These molecules were screened in vitro for their antifungal and antibacterial activity, and none of the tested compounds showed promising antimicrobial or antifungal activity.

Item Type:	Article
Subjects:	Chemical Sciences
Divisions:	UNSPECIFIED
Depositing User:	Mr. Amit Nargotra
Date Deposited:	03 Jan 2012 05:03
Last Modified:	03 Jan 2012 05:03
URI:	http://iiim.csircentral.net/id/eprint/351

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