Bani, Sarang and Kaul, Anpurna and Khan, Beenish and Gupta, Vijay Kumar and Satti, Naresh Kumar and Suri, Krishan Avtar and Qazi, Ghulam Nabi (2007) Anti-arthritic activity of a biopolymeric fraction from Euphorbia tirucalli. Journal of Ethnopharmacology, 110 (1). pp. 92-98. ISSN 03788741

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Abstract

The present study was undertaken to investigate the anti-arthritic activity of a biopolymeric fraction (BET) from plant Euphorbia tirucalli Boiss (Euphorbiaceae). The fraction showed dose dependent anti-arthritic activity and also showed in vivo immunomodulatory capacity being a major component in inhibiting arthritis. It caused suppression of CD4+ and CD8+ T cells, inhibition of intracellular Interleukin-2 (IL-2) and Interferon-gamma (IFN-�) by flowcytometry. It inhibited vascular permeability and the migration of leucocytes at the site of the insult. The oral LD0 in both rats and mice was more than 2000 mg/kg.

Item Type:	Article
Subjects:	Pharmacological Sciences
Divisions:	UNSPECIFIED
Depositing User:	Mr. Amit Nargotra
Date Deposited:	28 Dec 2011 06:20
Last Modified:	28 Dec 2011 06:20
URI:	http://iiim.csircentral.net/id/eprint/210

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