AHMAD, K and TANEJA, S and SINGH, A and ANAND, N and QURISHI, M and KOUL, S and QAZI, G (2007) A chemo-enzymatic route to diastereoisomers of 2-methyl-1-phenyl-1,3-butanediol: the dual role of microorganisms. Tetrahedron, 63 (2). pp. 445-450. ISSN 00404020
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Abstract
Diastereoisomers (1S,2R,3S)-, (1R,2R,3S)-, (1R,2S,3S)- and (1S,2S,3S)-2-methyl-1-phenyl-1,3-butanediols were prepared by simple and convenient strategies using two different chemo-enzymatic approaches for the reduction of racemic 2-methyl-1-phenyl-1,3-butanedione,both involving in situ racemization. The first method comprised a one-pot microbial reduction coupled with a chemical reduction, while in the second method, stepwise chemo-enzymatic reductions were performed.
| Item Type: | Article |
|---|---|
| Subjects: | Chemical Sciences |
| Divisions: | UNSPECIFIED |
| Depositing User: | Mr. Amit Nargotra |
| Date Deposited: | 19 Dec 2011 07:10 |
| Last Modified: | 19 Dec 2011 07:10 |
| URI: | http://iiim.csircentral.net/id/eprint/182 |
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