AHMAD, K and TANEJA, S and SINGH, A and ANAND, N and QURISHI, M and KOUL, S and QAZI, G (2007) A chemo-enzymatic route to diastereoisomers of 2-methyl-1-phenyl-1,3-butanediol: the dual role of microorganisms. Tetrahedron, 63 (2). pp. 445-450. ISSN 00404020

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Diastereoisomers (1S,2R,3S)-, (1R,2R,3S)-, (1R,2S,3S)- and (1S,2S,3S)-2-methyl-1-phenyl-1,3-butanediols were prepared by simple and convenient strategies using two different chemo-enzymatic approaches for the reduction of racemic 2-methyl-1-phenyl-1,3-butanedione,both involving in situ racemization. The first method comprised a one-pot microbial reduction coupled with a chemical reduction, while in the second method, stepwise chemo-enzymatic reductions were performed.

Item Type: Article
Subjects: Chemical Sciences
Depositing User: Mr. Amit Nargotra
Date Deposited: 19 Dec 2011 07:10
Last Modified: 19 Dec 2011 07:10
URI: http://iiim.csircentral.net/id/eprint/182

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