Sampath Kumar, H.M. and Singh, Parvinder Pal and Shafi, Syed and Reddy, Pitta Bhaskar and Shravankumar, Kankala and Reddy, Doma Mahender (2007) Reaction of allenylmagnesium and allenylindium bromides with nitrile oxides: synthesis of novel 5-butynyl- and 5-methylisoxazoles. Tetrahedron Letters, 48 (5). pp. 887-890. ISSN 00404039

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5-Butynylisoxazoles were obtained in high yields through a domino addition, C–O heterocyclization involving allenylmagnesium bromide and benzonitrile oxide in dry THF, in which the corresponding 5-methylisoxazoles were isolated in trace amounts. However, when the reactions were attempted in aqueous media using allenylindium bromide, 5-methylisoxazoles were formed as the sole products in high yields.

Item Type: Article
Subjects: Chemical Sciences
Depositing User: Mr. Amit Nargotra
Date Deposited: 02 Jan 2012 12:06
Last Modified: 02 Jan 2012 12:06

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