Shah, Bhahwal Ali and Chib, Renu and Anand, Naveen and Pandey, Anjali and Kapoor, Kamini and Bani, Sarang and Gupta, Vivek K. and K, Rajnikant and Sethi, Vijay K. and Taneja, Subhash Chandra (2011) Psilostachyin, acetylated pseudoguaianolides and their analogues: Preparation and evaluation of their anti-inflammatory potential. Bioorganic & Medicinal Chemistry Letters, 21 (16). pp. 4847-4851. ISSN 0960894X

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Abstract

Naturally occurring acetylated pseudoguaianolides and psilostachyin including their analogues were synthesized. The structure of semi-synthetic psilostachyin was also confirmed by X-ray crystallography. The anti-inflammatory potential of all the derivatives has been evaluated through in vitro expression of TNF-a, IL-1b and IL-6 in murine neutrophils.

Item Type:	Article
Subjects:	Chemical Sciences
Divisions:	UNSPECIFIED
Depositing User:	Mr. Amit Nargotra
Date Deposited:	27 Dec 2011 12:06
Last Modified:	27 Dec 2011 12:06
URI:	http://iiim.csircentral.net/id/eprint/320

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