Kitchlu, S. and Ram, G. and Koul, Sushma and Koul, Kiran and Gupta, K.K. and Ahuja, Ashok (2011) Podophyllum lignans array of Podophyllum hexandrum Royle populations from semi-desert alpine region of Zanskar valley in Himalayas. Industrial Crops and Products, 33 (3). pp. 584-587. ISSN 09266690

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Podophyllum hexandrum Royle (Syn. P. emodi Wale) a perennial rhizomatous herb found in alpine region distributed in the entire range of Himalayas from Ladakh to Sikkim at an altitude of 3000–4200masl is an preferred commercial source of Podophyllum lignans. It contains three times more Podophyllotoxin than the American species, Podophyllum peltatum. The present study was aimed to investigate variation of Podophyllum lignans contents based on six marker compounds viz. Podophyllotoxin; Deoxypodophyllotoxin;Picropodophyllotoxin; Podophyllotoxin �-d-glucopyanoside; Isopicropodophyllone; 4�-Demethyldeoxypodophyllotoxin, �-d-lucopyanoside, in P. hexandrum population growing at three locations. Further, ontogenetic and morphogenetic variations of Podophyllum lignan contents were studied to investigate dynamics of accumulation of these compounds. Representative collections from three locations viz., Panikhar, Padam and Tangoli located in Trans Himalayan semi-desert region of Zanskar valley were harvested at three stages (dormancy, active growth and maturity). Plants were dissected into root, rhizome and rhizome-buds, dried separately and assayed for Podophyllum lignan contents by high performance liquid chromatography.

Item Type: Article
Subjects: Biological Sciences
Depositing User: Mr. Amit Nargotra
Date Deposited: 02 Jan 2012 11:15
Last Modified: 02 Jan 2012 11:15

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