Shah, Bhahwal A. and Kumar, Ajay and Gupta, Pankaj and Sharma, Madhunika and Sethi, Vijay K. and Saxena, Ajit K. and Singh, Jaswant and Qazi, Ghulam N. and Taneja, Subhash C. (2007) Cytotoxic and apoptotic activities of novel amino analogues of boswellic acids. Bioorganic & Medicinal Chemistry Letters, 17 (23). pp. 6411-6416. ISSN 0960894X

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Abstract

4-Amino analogues prepared from b-boswellic acid and 11-keto-b-boswellic acid, wherein the carboxyl group in ursane nucleus was replaced by an amino function via Curtius reaction, displayed improved cytotoxicity than the parent molecules. The same molecules also exhibited apoptotic activity by inducing DNA fragmentation.

Item Type:	Article
Subjects:	Chemical Sciences Pharmacological Sciences
Divisions:	UNSPECIFIED
Depositing User:	Mr. Amit Nargotra
Date Deposited:	28 Dec 2011 08:24
Last Modified:	28 Dec 2011 08:24
URI:	http://iiim.csircentral.net/id/eprint/235

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