Gupta, Pankaj and Shah, Bhahwal Ali and Parshad, Rajinder and Qazi, Ghulam Nabi and Taneja, Subhash Chandra (2007) A facile approach towards enantiomerically pure masked β-amino alcohols. Green Chemistry, 9 (10). p. 1120. ISSN 1463-9262

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b-Amino alcohols are bioactive molecules, used also as catalysts in asymmetric C–C bond formation. While asymmetric synthesis has been the preferred route for their preparation, there was always been a need to develop a facile methodology involving environmentally friendly transformations. Masked amines in the form of phthalimide alcohols, prepared via a fast coupling reaction in an ionic liquid as a reusable reaction media together with reduction and an efficient biocatalytic resolution, offer a green methodology for enantiomerically pure products(ee . 99%, 50 g L21).

Item Type: Article
Subjects: Chemical Sciences
Depositing User: Mr. Amit Nargotra
Date Deposited: 19 Dec 2011 07:33
Last Modified: 19 Dec 2011 07:33

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